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KMID : 0359720090270020123
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Journal of the Korean Neurological Association
2009 Volume.27 No. 2 p.123 ~ p.128
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Influence of Stroke Knowledge on Pre-hospital Delay of Acute Ischemic Stroke Patients
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Lee Jae-Jin
Kim Hoo-Won
Kim Jin-Ho
Ahn Seong-Hwan
Choo In-Sung
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Abstract
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Background: Most stroke patients are unable to receive thrombolytic therapy because they do not reach a hospital within 3 hours from symptom onset. The aim of this study was to determine the factors (including knowledge of stroke) that affect the admission delay.
Methods: From May 2007 to December 2007, consecutive ischemic stroke patients presenting within 3 days from symptom onset and their relatives were interviewed about their knowledge of the following aspects of stroke: stroke warning signs, thrombolytic therapy, the 3-hour time limit for admission delay, and use of emergency medical services. Clinical data of patients were collected from medical records.
Results: One hundred and fifty-three patients were finally included, 37 of which (24.2%) reached our hospital within 3 hours from symptom onset. In univariate and multivariate analyses, factors independently associated with an admission delay of less than 3 hours were age (odds ratio [OR]=0.95, 95% confidence interval [CI]=0.91?0.99; p=0.008), atrial fibrillation (OR=5.02, CI=1.35?18.70; p=0.016), NIHSS score at admission (OR=1.09, CI=1.01?1.18; p=0.028), and knowledge of the 3-hour time limit (OR=3.55, CI=1.45?8.72; p=0.006). In the patients with an NIHSS score of >4 points, knowledge of the 3-hour time limit was the only independent factor associated with an admission delay of less than 3 hours. This knowledge was significantly associated with graduation from high school (p=0.038).
Conclusions: Knowledge of the 3-hour time limit was the only modifiable factor that influenced an admission delay of less than 3 hours. Therefore, educating the public about stroke, including about the 3-hour time limit, could increase the ability to apply thrombolysis to acute stroke patients.
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KEYWORD
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Stroke, Thrombolysis, Emergency medical services, Education
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